Description

Methyl 2-Bromo-3-(1,3-Dioxolan-2-Yl)Benzoate is a high-value, multi-functional organic building block characterized by its bromo-substituted benzoate core protected by a dioxolane group. This compound matters as a critical synthetic intermediate, offering versatile reactivity for constructing complex molecular architectures in advanced chemical synthesis. It is primarily needed by research and development chemists and process scale-up teams within the pharmaceutical, agrochemical, and advanced material industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring functionalized benzoate or benzaldehyde derivatives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and protected aldehyde functionality.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where its aromatic and functional groups impart specific properties.
• Custom Synthesis and Contract Manufacturing: A vital component for custom chemical synthesis houses serving clients in drug discovery and specialty chemical production.
• Academic and Industrial R&D: Utilized in methodological development and exploratory chemistry within university laboratories and corporate R&D centers.

Basic Information

Product Name	Methyl 2-Bromo-3-(1,3-Dioxolan-2-Yl)Benzoate
CAS No.	1269411-36-0
Molecular Formula	C11H11BrO4
Molecular Weight	287.11 g/mol
Synonyms	2-Bromo-3-(1,3-dioxolan-2-yl)benzoic acid methyl ester; Methyl 2-bromo-3-(1,3-dioxolan-2-yl)benzoate; Benzoic acid, 2-bromo-3-(1,3-dioxolan-2-yl)-, methyl ester; 3-(1,3-Dioxolan-2-yl)-2-bromobenzoic acid methyl ester; Methyl 2-bromo-3-(2',2'-dimethyl-1,3-dioxolan-4-yl)benzoate (related protected form); 2-Bromo-3-(dioxolan-2-yl)methyl benzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-3-(1,3-Dioxolan-2-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.