Description

Ethyl 1-(3-Chlorophenyl)-5-Fluoro-1H-Pyrazole-4-Carboxylate is a high-purity fluorinated pyrazole derivative, a critical advanced intermediate in modern synthetic chemistry. Its value lies in its versatile molecular scaffold, which is engineered for the efficient synthesis of complex, biologically active molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it serves as a key building block for new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Serves as a core building block for creating new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty chemicals, advanced polymers, and functional materials that require fluorinated heterocyclic components.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tagging reagent in biochemical research due to its reactive ester group and fluorine atom.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects requiring fluoropyrazole chemistry.

Basic Information

Product Name	Ethyl 1-(3-Chlorophenyl)-5-Fluoro-1H-Pyrazole-4-Carboxylate
CAS No.	1269292-55-8
Molecular Formula	C12H10ClFN2O2
Molecular Weight	268.67 g/mol
Synonyms	Ethyl 5-Fluoro-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylate; 1-(3-Chlorophenyl)-5-fluoro-1H-pyrazole-4-carboxylic Acid Ethyl Ester; 5-Fluoro-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester; 1269292-55-8; 3-Chloro-5-fluoropyrazole-4-carboxylate ethyl ester derivative; 1H-Pyrazole-4-carboxylic acid, 1-(3-chlorophenyl)-5-fluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 1-(3-Chlorophenyl)-5-Fluoro-1H-Pyrazole-4-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and MS analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.