Description

Ethyl 1-(Aminomethyl)Cyclobutane-1-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant building block used in the synthesis of complex organic molecules. This compound matters as a versatile intermediate, offering a functionalized cyclobutane scaffold with both ester and primary amine hydrochloride functionalities, enabling diverse chemical transformations. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and exploring new chemical spaces. Its specific structure makes it valuable for medicinal chemistry programs targeting constrained analogs and for developing advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating constrained peptide mimetics and small molecule libraries.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require a rigid, functionalized cyclobutane core.
• Chemical Synthesis: Serves as a versatile precursor for further derivatization, including amide coupling, reduction, and hydrolysis reactions to access a variety of cyclobutane derivatives.
• Material Science: Potential monomer or cross-linking agent in the research of specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting research in organic methodology and complex molecule synthesis.

Basic Information

Item	Details
Product Name	Ethyl 1-(Aminomethyl)Cyclobutane-1-Carboxylate Hydrochloride
CAS No.	1269021-92-2
Molecular Formula	C9H18ClNO2
Molecular Weight	207.70 g/mol
Synonyms	1-(Aminomethyl)cyclobutane-1-carboxylic acid ethyl ester hydrochloride; Ethyl 1-(aminomethyl)cyclobutanecarboxylate hydrochloride; 1-Carbethoxy-1-aminomethylcyclobutane hydrochloride; Cyclobutanecarboxylic acid, 1-(aminomethyl)-, ethyl ester, hydrochloride; Ethyl 1-aminomethylcyclobutane-1-carboxylate HCl; 1-(Ethoxycarbonyl)-1-(aminomethyl)cyclobutane hydrochloride; 1-(Aminomethyl)cyclobutyl-1-carboxylic acid ethyl ester HCl
EINECS	Contact for details

Quality Control

Our Ethyl 1-(Aminomethyl)Cyclobutane-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.