Description

Olorinab is a potent and selective agonist of the cannabinoid receptor 2 (CB2), representing a significant compound in pharmaceutical research and development. Its targeted mechanism of action makes it a valuable tool for investigating inflammatory and pain pathways, offering potential for novel therapeutic applications. This high-purity compound is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors focused on neurobiology, immunology, and analgesic drug discovery.

Application

• Pharmaceutical R&D: Primary use as a reference standard and active pharmaceutical ingredient (API) in preclinical and clinical research for pain and inflammation.
• Mechanistic Studies: A critical tool compound for studying CB2 receptor signaling, function, and its role in the endocannabinoid system.
• Drug Discovery Programs: Serves as a lead compound or benchmark for developing new CB2-targeted therapeutics for conditions like neuropathic pain, inflammatory bowel disease (IBD), and multiple sclerosis.
• Biochemical Assay Development: Used in high-throughput screening (HTS) and in vitro assays to identify and characterize other CB2 receptor modulators.
• Academic Research: Employed in university and institutional labs for fundamental research in neuroscience, immunology, and pharmacology.

Basic Information

Product Name	Olorinab
CAS No.	1268881-20-4
Molecular Formula	C₂₀H₂₀F₃N₃O₂
Molecular Weight	391.39 g/mol
Synonyms	APD371; (R)-3-(1-(4-Chlorophenyl)ethyl)-6-(4-(trifluoromethyl)phenyl)pyridazin-4(1H)-one; (R)-APD371; CB2 Receptor Agonist APD371; 4(1H)-Pyridazinone, 3-[1-(4-chlorophenyl)ethyl]-6-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our Olorinab is manufactured under strict quality management systems to ensure the highest standards of purity and consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support your regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.