Description

1-[(Trimethylsilyl)Ethynyl]Cyclobutanecarboxylic Acid is a high-value organosilicon building block featuring a cyclobutane ring and a protected acetylene moiety. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists exploring new polymers and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of cyclobutane-containing drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides with unique modes of action.
• Material Science Research: Serves as a precursor for silicon-containing polymers and advanced organic frameworks with tailored properties.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Ligand and Catalyst Development: The trimethylsilylethynyl group acts as a versatile handle for creating sophisticated ligands for catalysis.
• Academic & Industrial R&D: A versatile building block for exploratory chemistry in both university laboratories and corporate R&D centers.

Basic Information

Product Name	1-[(Trimethylsilyl)Ethynyl]Cyclobutanecarboxylic Acid
CAS No.	1268810-14-5
Molecular Formula	C10H16O2Si
Molecular Weight	196.32 g/mol
Synonyms	Cyclobutanecarboxylic acid, 1-[(trimethylsilyl)ethynyl]-; 1-(Trimethylsilylethynyl)cyclobutanecarboxylic acid; 1-(2-Trimethylsilylethynyl)cyclobutanecarboxylic acid; 1-(Trimethylsilylethynyl)cyclobutane-1-carboxylic acid; TMS-Ethynyl Cyclobutanecarboxylic Acid; (1-Carboxycyclobutyl)ethynyltrimethylsilane; 1268810-14-5
EINECS	Contact for details

Quality Control

Our production of 1-[(Trimethylsilyl)Ethynyl]Cyclobutanecarboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to supplying material that meets the exacting requirements of process chemistry and advanced synthetic programs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.