Description

(Cyclobutylethynyl)Trimethylsilane is a specialized organosilicon building block featuring a cyclobutyl ring and a protected ethynyl group. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications in medicinal chemistry and functional material development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for cyclobutane-containing drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for silicon-containing polymers, dendrimers, and advanced organic electronic materials.
• Cross-Coupling Reactions: The trimethylsilyl-protected alkyne moiety is a valuable handle for Sonogashira and other palladium-catalyzed coupling reactions.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic complexes for catalytic applications.
• Academic & Industrial R&D: A critical reagent for methodology development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	(Cyclobutylethynyl)Trimethylsilane
CAS No.	1268810-13-4
Molecular Formula	C9H16Si
Molecular Weight	152.31 g/mol
Synonyms	Trimethyl((cyclobutylethynyl))silane; Cyclobutyl(trimethylsilyl)acetylene; (Cyclobutylethynyl)trimethylsilicon; Cyclobutylacetylene, trimethylsilyl-; 1-(Trimethylsilyl)ethynylcyclobutane; (Cyclobut-1-ylethynyl)trimethylsilane; Cyclobutyl ethynyl trimethyl silane
EINECS	Contact for details

Quality Control

Our production of (Cyclobutylethynyl)Trimethylsilane adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming the product meets the agreed specifications for your research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.