Description

(R)-Methyl 3-Methyl-2-(Methylamino)Butanoate Hydrochloride is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters because it provides a stereochemically defined scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). Pharmaceutical research and fine chemical synthesis laboratories need it for creating novel therapeutic candidates, including peptidomimetics and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new Active Pharmaceutical Ingredients (APIs), especially for neurological and metabolic disorders.
• Peptidomimetic Synthesis: Used to introduce a constrained, methylated amino acid moiety into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel catalytic systems for stereoselective transformations.
• Agrochemical Development: Employed in the synthesis of chiral active ingredients for advanced crop protection agents.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for methodological studies in organic and medicinal chemistry.
• Custom Synthesis Building Block: Provides a versatile starting material for contract manufacturing organizations (CMOs) engaged in producing complex, custom molecules for clients.

Basic Information

Product Name	(R)-Methyl 3-Methyl-2-(Methylamino)Butanoate Hydrochloride
CAS No.	1268729-60-7
Molecular Formula	C8H18ClNO2
Molecular Weight	195.69 g/mol
Synonyms	Methyl (2R)-3-methyl-2-(methylamino)butanoate hydrochloride; (R)-Methyl 2-(Methylamino)-3-methylbutyrate Hydrochloride; L-Valine, N-methyl-, methyl ester, hydrochloride, (2R)-; Methyl N-methyl-L-valinate hydrochloride; (R)-Methyl N-methylvalinate HCl; (2R)-3-Methyl-2-(methylamino)butanoic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Methyl 3-Methyl-2-(Methylamino)Butanoate Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.