Description

1-Isopropyl-1,4-Dihydrospiro[Indazole-5,4'-Piperidin]-7(6H)-One CAS NO 1268521-75-0 is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic indazole-piperidine hybrid structure. This compound is of significant commercial interest for its role as a critical building block in modern drug discovery and development programs. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in synthesizing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Scaffold: Utilized in medicinal chemistry for constructing compound libraries and exploring structure-activity relationships (SAR) due to its privileged spirocyclic architecture.
• CNS-Targeted Research: Serves as a core structure for developing potential therapeutics targeting neurological disorders.
• Oncology Research: Employed in the synthesis of experimental compounds for investigating novel anti-cancer mechanisms.
• Chemical Biology Probe: Used as a tool compound to study specific biological pathways and protein interactions.
• Process Chemistry Development: Serves as a reference standard and starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	1-Isopropyl-1,4-Dihydrospiro[Indazole-5,4'-Piperidin]-7(6H)-One
CAS No.	1268521-75-0
Molecular Formula	C14H19N3O
Molecular Weight	245.32 g/mol
Synonyms	1-Isopropyl-1,4-dihydrospiro[indazole-5,4'-piperidin]-7(6H)-one; 1-Isopropyl-6,7-dihydro-4H-spiro[indazole-5,4'-piperidin]-7-one; Spiro[indazole-5,4'-piperidine]-7(6H)-one, 1,4-dihydro-1-(1-methylethyl)-; 1268521-75-0; 1-(Propan-2-yl)-1,4-dihydrospiro[indazole-5,4'-piperidine]-7(6H)-one; 1-Isopropyl-1,4-dihydro-6H-spiro[indazole-5,4'-piperidin]-7-one
EINECS	Contact for details

Quality Control

Our production of 1-Isopropyl-1,4-Dihydrospiro[Indazole-5,4'-Piperidin]-7(6H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material produced under quality systems designed to meet the standards of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.