Description

6-Bromo-1'-Methyl-2H-Spiro[Benzofuran-3,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its spirocyclic piperidine core.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying biological pathways and target engagement.
• Custom Synthesis: Supplied to companies requiring bespoke, high-complexity intermediates for proprietary development pipelines.

Basic Information

Product Name	6-Bromo-1'-Methyl-2H-Spiro[Benzofuran-3,4'-Piperidine]
CAS No.	1268521-25-0
Molecular Formula	C13H16BrNO
Molecular Weight	282.18 g/mol
Synonyms	6-Bromo-1'-methyl-2H-spiro[benzofuran-3,4'-piperidine]; 2H-Spiro[benzofuran-3,4'-piperidine], 6-bromo-1'-methyl-; 6-Bromo-1'-methylspiro[benzofuran-3,4'-piperidine]; 1268521-25-0; Spiro[benzofuran-3(2H),4'-piperidine], 6-bromo-1'-methyl-
EINECS	Contact for details

Quality Control

Our 6-Bromo-1'-Methyl-2H-Spiro[Benzofuran-3,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.