Description

4-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors focused on innovation and process development.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials and ligands for catalysis.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services (CDMO/CMO).

Basic Information

Product Name	4-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1268520-92-8
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	1-Methyl-4-chloro-1H-pyrazolo[3,4-b]pyridine; 4-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 4-chloro-1-methyl-; 4-Chloro-1-methylpyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and compliance with REACH ensures a reliable supply for global regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.