Description

5-tert-Butyl 7-Ethyl 5-Azaspiro[2.4]Heptane-5,7-Dicarboxylate is a high-value, synthetically versatile spirocyclic building block used in advanced organic synthesis. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and fine chemicals, where its unique constrained spiro structure enables the exploration of new chemical space. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and as a key intermediate for creating complex molecular architectures with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its spirocyclic framework for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Chemical Biology: Employed as a molecular probe or scaffold in the study of protein-ligand interactions and enzyme inhibition.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for contract research organizations (CROs) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	5-tert-Butyl 7-Ethyl 5-Azaspiro[2.4]Heptane-5,7-Dicarboxylate
CAS No.	1268520-72-4
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	5-Azaspiro[2.4]heptane-5,7-dicarboxylic acid, 5-(1,1-dimethylethyl) 7-ethyl ester; 5-tert-Butyl 7-ethyl 5-azaspiro[2.4]heptane-5,7-dicarboxylate; Ethyl 5-tert-butyl 5-azaspiro[2.4]heptane-5,7-dicarboxylate; 7-Ethyl 5-tert-butyl 5-azaspiro[2.4]heptane-5,7-dicarboxylate; Spirocyclic ester intermediate 1268520-72-4; tert-Butyl ethyl 5-azaspiro[2.4]heptane-5,7-dicarboxylate
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl 7-Ethyl 5-Azaspiro[2.4]Heptane-5,7-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.