Description

4-(Bromomethyl)-2-(Difluoromethoxy)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is particularly valued for its reactive bromomethyl group and the electron-withdrawing difluoromethoxy substituent, which enable precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel pyridine-based ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials due to its halogenated structure.
• Chemical Biology Probes: Useful for the design and synthesis of molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(Bromomethyl)-2-(Difluoromethoxy)Pyridine
CAS No.	1268517-84-5
Molecular Formula	C7H6BrF2NO
Molecular Weight	238.03 g/mol
Synonyms	2-(Difluoromethoxy)-4-(bromomethyl)pyridine; 4-(Bromomethyl)-2-difluoromethoxypyridine; 2-Difluoromethoxy-4-bromomethylpyridine; Pyridine, 4-(bromomethyl)-2-(difluoromethoxy)-; 1268517-84-5; 4-Bromomethyl-2-difluoromethoxypyridine
EINECS	Contact for details

Quality Control

Every batch of 4-(Bromomethyl)-2-(Difluoromethoxy)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.