Description

2-Methyl-5-(2-Methyl-1,3-Oxazol-5-Yl)Benzenesulfonyl Chloride CAS NO 1268334-77-5 is a high-purity sulfonyl chloride derivative, a critical building block in modern organic synthesis. Its value lies in its role as a versatile electrophilic reagent for introducing the sulfonamide functional group, which is pivotal for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly those focused on developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting enzyme inhibition where the sulfonamide moiety is crucial.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactivity to create potent active ingredients.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling or modifying proteins and other biomolecules in research applications.
• Material Science Research: Employed in the creation of specialty polymers and functional materials that require sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs offering bespoke synthetic routes for client molecules.
• Library Synthesis for High-Throughput Screening: Used to rapidly generate diverse compound libraries for drug discovery campaigns.

Basic Information

Product Name	2-Methyl-5-(2-Methyl-1,3-Oxazol-5-Yl)Benzenesulfonyl Chloride
CAS No.	1268334-77-5
Molecular Formula	C12H12ClNO3S
Molecular Weight	285.75 g/mol
Synonyms	5-(2-Methyl-1,3-oxazol-5-yl)-2-methylbenzenesulfonyl chloride; 2-Methyl-5-(2-methyloxazol-5-yl)benzenesulfonyl chloride; 2-Methyl-5-(2-methyl-1,3-oxazol-5-yl)benzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 2-methyl-5-(2-methyl-5-oxazolyl)-; 1268334-77-5; 2-Methyl-5-(2-methyloxazol-5-yl)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(2-Methyl-1,3-Oxazol-5-Yl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.