Description

tert-Butyl 12-Oxo-3,7,11-Triazaspiro[5.6]Dodecane-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the development of innovative therapeutics, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or other complex disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential component for constructing linkers or ligands in the design of targeted protein degraders.
• Chemical Biology Tool Development: Employed in the synthesis of molecular probes for studying enzyme function or protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	tert-Butyl 12-Oxo-3,7,11-Triazaspiro[5.6]Dodecane-3-Carboxylate
CAS No.	1268334-76-4
Molecular Formula	C14H25N3O3
Molecular Weight	283.37 g/mol
Synonyms	tert-Butyl 12-oxo-3,7,11-triazaspiro[5.6]dodecane-3-carboxylate; 3,7,11-Triazaspiro[5.6]dodecane-3-carboxylic acid, 12-oxo-, 1,1-dimethylethyl ester; 12-Oxo-3,7,11-triazaspiro[5.6]dodecane-3-carboxylic acid tert-butyl ester; tert-Butyl 12-oxo-3,7,11-triazaspiro[5.6]dodecane-3-carboxylate; 1268334-76-4; CAS 1268334-76-4
EINECS	Contact for details

Quality Control

Our tert-Butyl 12-Oxo-3,7,11-Triazaspiro[5.6]Dodecane-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.