Description

4-Methyl-6-(trifluoromethyl)-2-pyridinamine is a high-purity, functionalized pyridine derivative characterized by its trifluoromethyl and amine substituents. This compound is a valuable pharmaceutical intermediate and agrochemical building block, prized for its ability to impart metabolic stability and lipophilicity to target molecules. It is primarily utilized by R&D chemists and process development scientists in the life sciences and crop protection industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a crucial building block for novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Used in the development of advanced organic materials, including ligands for catalysis and monomers for specialty polymers.
• Chemical Biology & Proteomics: Employed as a molecular tag or a component of chemical probes for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines for clinical trials.

Basic Information

Product Name	4-Methyl-6-(Trifluoromethyl)-2-Pyridinamine
CAS No.	1267496-45-6
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	2-Amino-4-methyl-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-4-methylpyridin-2-amine; 4-Methyl-6-trifluoromethylpyridin-2-ylamine; 4-Methyl-6-(trifluoromethyl)-2-aminopyridine; 2-Pyridinamine, 4-methyl-6-(trifluoromethyl)-; 4-Methyl-6-(trifluoromethyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-6-(trifluoromethyl)-2-pyridinamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and GC-MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.