Description

5-(2-Chlorophenyl)Pyridine-3-Carbonitrile is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a chlorophenyl and a nitrile-substituted pyridine ring, makes it a critical intermediate for constructing complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Development: Used in research to create new herbicides, fungicides, and insecticides with targeted modes of action.
• Ligand Synthesis: Serves as a starting material for constructing complex chelating ligands used in catalysis and material science.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	5-(2-Chlorophenyl)Pyridine-3-Carbonitrile
CAS No.	1267467-92-4
Molecular Formula	C12H7ClN2
Molecular Weight	214.65 g/mol
Synonyms	3-Cyano-5-(2-chlorophenyl)pyridine; 5-(2-Chlorophenyl)-3-pyridinecarbonitrile; 2-Chloro-5-cyanophenylpyridine; (2-Chlorophenyl)-3-cyanopyridine; 5-(o-Chlorophenyl)nicotinonitrile; Pyridine-3-carbonitrile, 5-(2-chlorophenyl)-; 1267467-92-4
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Chlorophenyl)Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.