Description

5-(3-Chlorophenyl)Pyridine-3-Carbonitrile is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine-chlorophenyl scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs (Organic Light-Emitting Diodes) or conductive polymers.
• Chemical Biology Probe: Utilized as a core structure for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke chemicals and non-commercial quantities for research.

Basic Information

Product Name	5-(3-Chlorophenyl)Pyridine-3-Carbonitrile
CAS No.	1266996-42-2
Molecular Formula	C12H7ClN2
Molecular Weight	214.65 g/mol
Synonyms	3-Cyano-5-(3-chlorophenyl)pyridine; 5-(3-Chlorophenyl)-3-pyridinecarbonitrile; 3-Chlorophenyl-3-cyanopyridine; 3-Pyridinecarbonitrile, 5-(3-chlorophenyl)-; 5-(3-Chlorophenyl)nicotinonitrile; 5-(m-Chlorophenyl)pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-(3-Chlorophenyl)Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.