Description

Imidazo[1,2-A]Pyridine, 5-Chloro-7-Iodo- CAS NO 1266656-98-7 is a high-purity halogenated heterocyclic compound belonging to the imidazopyridine class. This advanced pharmaceutical intermediate is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the development of new drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its unique halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it a valuable substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis for High-Throughput Screening: Employed in combinatorial chemistry to generate diverse compound libraries for biological screening.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine, 5-Chloro-7-Iodo-
CAS No.	1266656-98-7
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	5-Chloro-7-iodoimidazo[1,2-a]pyridine; 7-Iodo-5-chloroimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 5-chloro-7-iodo-; 5-Chloro-7-iodo-imidazo[1,2-a]pyridine; SCHEMBL23545427; AKOS040759623; ZINC000257803716; 1266656-98-7
EINECS	Contact for details

Quality Control

Every batch of Imidazo[1,2-A]Pyridine, 5-Chloro-7-Iodo- is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile by HPLC, NMR, and mass spectrometry is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.