Description

6-Fluoro-4-Methylnicotinaldehyde is a high-purity fluorinated nicotinaldehyde derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a reactive aldehyde group and a substituted pyridine core, enabling the construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional dyes due to its conjugated system.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for biochemical research.
• Custom Synthesis and R&D: A versatile starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	6-Fluoro-4-Methylnicotinaldehyde
CAS No.	1266253-68-2
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	4-Methyl-6-fluoronicotinaldehyde; 6-Fluoro-4-methyl-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 6-fluoro-4-methyl-; 6-Fluoro-4-picolinaldehyde; 6-Fluoro-4-methylpyridine-3-carbaldehyde; 4-Methyl-6-fluoropyridine-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Methylnicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.