Description

2-Azido-1,3-Dimethylimidazolinium Hexafluorophosphate is a specialized organic salt widely recognized as a highly effective coupling reagent in peptide synthesis and other amide bond-forming reactions. Its primary value lies in its ability to facilitate rapid and high-yielding condensations under mild conditions, minimizing racemization and side reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries engaged in the development and production of peptides, peptidomimetics, and complex organic molecules.

Application

• Primary reagent for peptide coupling in solid-phase and solution-phase synthesis.
• Facilitates amide bond formation in the synthesis of complex pharmaceuticals and natural products.
• Used in the preparation of active pharmaceutical ingredients (APIs) and intermediates.
• Employed in bioconjugation techniques for labeling proteins and other biomolecules.
• Valuable reagent in medicinal chemistry research for library synthesis and lead optimization.
• Applicable in material science for creating specialized polymers and functional surfaces.

Basic Information

Product Name	2-Azido-1,3-Dimethylimidazolinium Hexafluorophosphate
CAS No.	1266134-54-6
Molecular Formula	C5H9N6·PF6
Molecular Weight	298.14 g/mol
Synonyms	ADMP; 2-Azido-1,3-dimethyl-2-imidazolinium hexafluorophosphate; 1,3-Dimethyl-2-azidoimidazolinium hexafluorophosphate; ADMP-HFP; Azido-Dimethylimidazolinium PF6; Coupling Reagent ADMP
EINECS	Contact for details

Quality Control

Our 2-Azido-1,3-Dimethylimidazolinium Hexafluorophosphate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and production applications. Each lot is analyzed with modern analytical techniques, including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.