Description

tert-Butyl n-(4-Aminopyridin-2-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group on a pyridine scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors engaged in developing targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for the production of active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the development of labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	tert-Butyl n-(4-Aminopyridin-2-Yl)Carbamate
CAS No.	1266119-48-5
Molecular Formula	C10H15N3O2
Molecular Weight	209.25 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)-4-aminopyridine; 4-Amino-2-((tert-butoxycarbonyl)amino)pyridine; tert-Butyl (4-amino-2-pyridinyl)carbamate; BOC-4-Amino-2-aminopyridine; 2-(Boc-amino)-4-aminopyridine; N-Boc-2,4-diaminopyridine; tert-Butyl N-(4-aminopyridin-2-yl)carbamate; 1266119-48-5
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(4-Aminopyridin-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.