Description

1-Piperidinecarboxylic Acid, 4-(6-Chloro-2-Pyridinyl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific molecular architecture enables key chemical transformations. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel molecular libraries in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules.
• Chemical Biology Probes: Serves as a starting material for synthesizing labeled compounds or probes for biological target identification and validation.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-(6-Chloro-2-Pyridinyl)-, 1,1-Dimethylethyl Ester
CAS No.	1266118-78-8
Molecular Formula	C15H21ClN2O2
Molecular Weight	296.80 g/mol
Synonyms	tert-Butyl 4-(6-chloropyridin-2-yl)piperidine-1-carboxylate; 4-(6-Chloro-2-pyridinyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-4-(6-chloro-2-pyridyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(6-chloropyridin-2-yl)piperidine; 4-(6-Chloro-pyridin-2-yl)-piperidine-1-carboxylic acid tert-butyl ester; BOC-4-(6-Chloro-2-pyridinyl)piperidine; N-Boc-4-(6-chloropyridin-2-yl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-(6-Chloro-2-Pyridinyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.