Description

(S)-tert-Butyl 4-Hydroxy-2-Oxopiperidine-1-Carboxylate is a high-purity chiral piperidinone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, ensuring precise molecular architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• API Development: Used in research and process chemistry for constructing the core piperidinone structure found in various therapeutic agents.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers.
• Medicinal Chemistry Research: Serves as a versatile building block for creating focused libraries of compounds for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, agrochemicals, and other high-value materials requiring chiral purity.

Basic Information

Product Name	(S)-tert-Butyl 4-Hydroxy-2-Oxopiperidine-1-Carboxylate
CAS No.	1265900-08-0
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	(S)-1-Boc-4-Hydroxy-2-piperidinone; (S)-1-(tert-Butoxycarbonyl)-4-hydroxy-2-piperidinone; (S)-4-Hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-2-one; (S)-tert-Butyl 4-hydroxy-2-oxo-1-piperidinecarboxylate; (S)-Boc-4-Hydroxy-2-piperidinone; (S)-N-Boc-4-Hydroxy-2-piperidinone; (S)-1-N-Boc-4-hydroxy-2-piperidinone; 1,1-Dimethylethyl (4S)-4-hydroxy-2-oxo-1-piperidinecarboxylate
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 4-Hydroxy-2-Oxopiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.