Description

4-Bromo-2-(Tetrahydropyran-4-Yl)Pyridine is a high-value brominated pyridine derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining a halogenated pyridine core with a tetrahydropyran moiety, makes it an essential intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the bromine atom and the pyridine ring system offer sites for further functionalization.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	4-Bromo-2-(Tetrahydropyran-4-Yl)Pyridine
CAS No.	1264037-29-7
Molecular Formula	C10H12BrNO
Molecular Weight	242.11 g/mol
Synonyms	4-Bromo-2-(tetrahydro-2H-pyran-4-yl)pyridine; 2-(Oxan-4-yl)-4-bromopyridine; 4-Bromo-2-(4-tetrahydropyranyl)pyridine; 4-Bromo-2-(tetrahydropyran-4-yl)pyridine; 4-Bromo-2-(4-pyranyl)pyridine; Pyridine, 4-bromo-2-(tetrahydro-2H-pyran-4-yl)-; 1264037-29-7
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Tetrahydropyran-4-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of high-purity material for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.