Description

1-Aminomethyl-Cyclopentanecarboxylic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a sterically hindered, N-protected cyclopentane scaffold for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel peptide mimetics, active pharmaceutical ingredients (APIs), and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially peptidomimetics and protease inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific bioactive properties.
• Peptide Chemistry: Serves as a constrained, non-proteinogenic amino acid analog in peptide backbone modification to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Acts as a monomer or precursor for specialized polymers and dendrimers with unique structural properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services targeting complex, high-value specialty chemicals.

Basic Information

Product Name	1-Aminomethyl-Cyclopentanecarboxylic Acid tert-Butyl Ester
CAS No.	1263378-41-1
Molecular Formula	C12H23NO2
Molecular Weight	213.32 g/mol
Synonyms	tert-Butyl 1-(aminomethyl)cyclopentanecarboxylate; 1-(Aminomethyl)cyclopentanecarboxylic Acid tert-Butyl Ester; 1-Carboxycyclopentylmethylamine tert-Butyl Ester; N-Boc-1-aminomethylcyclopentanecarboxylic Acid (common misnomer); Cyclopentanecarboxylic acid, 1-(aminomethyl)-, 1,1-dimethylethyl ester; (1-(Aminomethyl)cyclopentyl)carboxylic acid tert-butyl ester; Protected 1-aminomethylcyclopentane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-Aminomethyl-Cyclopentanecarboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, supporting cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.