Description

2-Benzyl-Decahydro-[2,6]Naphthyridine Dihydrochloride is a high-purity, complex heterocyclic amine salt used as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel pharmaceutical candidates, particularly in medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Synthesis: Used to create tool compounds for investigating biological pathways and target validation.
• Agrochemical Research: Employed as an intermediate in the synthesis of novel crop protection agents and pesticides.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and novel reaction studies.
• Custom Synthesis & Scale-Up: A starting material for custom manufacturing and process chemistry for pre-clinical and early-phase clinical material.

Basic Information

Product Name	2-Benzyl-Decahydro-[2,6]Naphthyridine Dihydrochloride
CAS No.	1263378-31-9
Molecular Formula	C19H28N2·2HCl
Molecular Weight	357.36 g/mol (free base: 284.44)
Synonyms	2-Benzyl-decahydro-2,6-naphthyridine dihydrochloride; Decahydro-2-benzyl-2,6-naphthyridine dihydrochloride; 2-Benzyl-1,2,3,4,4a,5,6,7,8,8a-decahydro-2,6-naphthyridine dihydrochloride; 2-Benzyl-decahydro-2,6-naphthyridine HCl salt; 2-Benzylperhydro-2,6-naphthyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Benzyl-Decahydro-[2,6]Naphthyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.