Description

Methyl 5-Bromo-2-Chloro-3-Methylbenzoate is a high-purity, multi-substituted benzoate ester derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its precise halogenation pattern makes it a valuable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated aromatic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile substrate for cross-coupling reactions (e.g., Suzuki, Stille), nucleophilic substitutions, and further functional group transformations in academic and industrial R&D labs.
• Ligand and Catalyst Development: Utilized for constructing complex, halogenated ligands for transition metal catalysis and organocatalysis.

Basic Information

Product Name	Methyl 5-Bromo-2-Chloro-3-Methylbenzoate
CAS No.	1263377-05-4
Molecular Formula	C10H10BrClO2
Molecular Weight	277.54 g/mol
Synonyms	Methyl 5-bromo-2-chloro-3-methylbenzoate; 5-Bromo-2-chloro-3-methylbenzoic acid methyl ester; Benzoic acid, 5-bromo-2-chloro-3-methyl-, methyl ester; 2-Chloro-5-bromo-3-methylbenzoic acid methyl ester; Methyl 2-chloro-5-bromo-3-methylbenzoate; 3-Methyl-5-bromo-2-chlorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Chloro-3-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.