Description

Methyl 2-Chloro-6-Formylpyridine-3-Carboxylate is a high-purity, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a formyl and an ester group on a chlorinated pyridine ring, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its modifiable aromatic system.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Detail
Product Name	Methyl 2-Chloro-6-Formylpyridine-3-Carboxylate
CAS No.	1263286-09-4
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	2-Chloro-6-formylpyridine-3-carboxylic acid methyl ester; Methyl 2-chloro-6-formylnicotinate; 3-Pyridinecarboxylic acid, 2-chloro-6-formyl-, methyl ester; 2-Chloro-6-formyl-3-pyridinecarboxylic acid methyl ester; Methyl 2-chloro-6-oxo-1,6-dihydropyridine-3-carboxylate (tautomer); 2-Chloro-6-formylnicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Chloro-6-Formylpyridine-3-Carboxylate is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.