Description

3,3-Dimethyl-2-Oxa-7-Aza-Spiro[4.5]Decan-1-One is a high-value, complex spirocyclic heterocyclic compound, identified by CAS NO 1263283-85-7. This molecule serves as a critical advanced intermediate in modern synthetic organic chemistry, prized for its rigid, three-dimensional structure which is instrumental in constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry and scaffold diversity are paramount.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and other therapeutic areas requiring complex heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the spirocyclic core can contribute to unique biological activity and selectivity.
• Ligand and Catalyst Synthesis: Employed as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties due to its constrained geometry.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Serves as a versatile linker or core component in the design of bifunctional molecules for targeted protein degradation.
• Academic & Process Chemistry: A valuable reagent for methodological studies and scale-up process development in organic synthesis laboratories.

Basic Information

Product Name	3,3-Dimethyl-2-Oxa-7-Aza-Spiro[4.5]Decan-1-One
CAS No.	1263283-85-7
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	3,3-Dimethyl-2-oxa-7-azaspiro[4.5]decan-1-one; 2-Oxa-7-aza-spiro[4.5]decan-1-one, 3,3-dimethyl-; 7-Aza-3,3-dimethyl-2-oxaspiro[4.5]decan-1-one; 3,3-Dimethyl-2-oxa-7-azaspiro[4.5]decanone; 1263283-85-7; Spirocyclic lactam intermediate
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-2-Oxa-7-Aza-Spiro[4.5]Decan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development projects with custom synthesis and scale-up capabilities, adhering to cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain optimal stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.