Description

2-Oxa-8-Azaspiro[4.5]Decane, 3-[(Methylthio)Methyl]-, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and manufacturing who require reliable, high-quality intermediates to accelerate drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique spirocyclic scaffold.
• Process Chemistry & Scale-up: Serves as a starting material or intermediate in the development of robust, scalable synthetic routes for API production under GMP conditions.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	2-Oxa-8-Azaspiro[4.5]Decane, 3-[(Methylthio)Methyl]-, Hydrochloride (1:1)
CAS No.	1263281-42-0
Molecular Formula	C10H19NOS · HCl
Molecular Weight	237.79 g/mol
Synonyms	3-[(Methylthio)methyl]-2-oxa-8-azaspiro[4.5]decane hydrochloride; 2-Oxa-8-azaspiro[4.5]decane, 3-[(methylthio)methyl]-, hydrochloride; 8-Aza-2-oxaspiro[4.5]decane, 3-[(methylthio)methyl]-, hydrochloride; 3-(Methylthiomethyl)-2-oxa-8-azaspiro[4.5]decane hydrochloride; 3-(Methylsulfanylmethyl)-2-oxa-8-azaspiro[4.5]decane hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Oxa-8-Azaspiro[4.5]Decane, 3-[(Methylthio)Methyl]-, Hydrochloride (1:1) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support development with custom synthesis and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and returned to storage immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.