Description

2-Fluoro-7-Aza-Spiro[3.5]Nonane is a high-value, nitrogen-containing spirocyclic building block featuring a fluorine substituent. This compound is of significant interest in modern pharmaceutical and agrochemical research due to its unique three-dimensional structure and the presence of a fluorine atom, which can dramatically influence a molecule's metabolic stability, lipophilicity, and binding affinity. It serves as a critical intermediate for medicinal chemists developing novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key scaffold for the synthesis of novel active pharmaceutical ingredients (APIs), especially for CNS-targeting drugs and kinase inhibitors.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve drug-like properties.
• Agrochemical Development: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function and biological pathways.
• Material Science: Potential precursor for advanced organic materials and ligands in catalysis.

Basic Information

Item	Details
Product Name	2-Fluoro-7-Aza-Spiro[3.5]Nonane
CAS No.	1263178-15-9
Molecular Formula	C8H14FN
Molecular Weight	143.20 g/mol
Synonyms	2-Fluoro-7-azaspiro[3.5]nonane; 7-Azaspiro[3.5]nonane, 2-fluoro-; 2-Fluoro-7-aza-spiro[3.5]nonane; 2-Fluoro-7-azaspiro[3.5]nonane; 2-Fluoro-7-aza-spiro[3.5]nonane hydrochloride (salt forms may exist); 2-Fluoro-7-azaspiro[3.5]nonane HCl; F-Spiro[3.5]nonane-7-amine derivative
EINECS	Contact for details

Quality Control

Our 2-Fluoro-7-Aza-Spiro[3.5]Nonane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable and consistent performance in your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.