Description

tert-Butyl 3-Amino-1-Oxa-7-Azaspiro[4.5]Decane-7-Carboxylate (Wx100552) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential therapeutic activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its constrained spirocyclic structure.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for potential drug molecules.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery programs.
• Chemical Biology Probes: Can be utilized to develop chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	tert-Butyl 3-Amino-1-Oxa-7-Azaspiro[4.5]Decane-7-Carboxylate (Wx100552)
CAS No.	1263177-13-4
Molecular Formula	C13H24N2O3
Molecular Weight	256.34 g/mol
Synonyms	7-Boc-3-amino-1-oxa-7-azaspiro[4.5]decane; tert-Butyl 3-amino-1-oxa-7-azaspiro[4.5]decane-7-carboxylate; 3-Amino-1-oxa-7-azaspiro[4.5]decane-7-carboxylic acid tert-butyl ester; 1-Oxa-7-azaspiro[4.5]decane-7-carboxylic acid, 3-amino-, 1,1-dimethylethyl ester; Wx100552; 1263177-13-4; Boc-protected 3-amino-1-oxa-7-azaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-1-Oxa-7-Azaspiro[4.5]Decane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.