Description

5-Bromo-2-tert-Butyloxycarbonylamino Pyridine-3-Boronic Acid Pinacol Ester is a high-value, multifunctional boronic ester derivative designed for advanced synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, enabling the precise construction of complex heterocyclic scaffolds essential for modern drug discovery. Pharmaceutical researchers and agrochemical developers need this reagent for creating novel active ingredients, particularly in the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new active ingredients with specific biological activity by constructing complex pyridine-based heterocycles.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the synthesis of chemical probes and affinity tags for studying protein function and interactions.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Catalyst Ligand Synthesis: Used to prepare sophisticated ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	5-Bromo-2-tert-Butyloxycarbonylamino Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1263142-42-2
Molecular Formula	C₁₇H₂₆BBrN₂O₄
Molecular Weight	413.12 g/mol
Synonyms	5-Bromo-2-((tert-butoxycarbonyl)amino)pyridine-3-boronic acid pinacol ester; 2-((tert-Butoxycarbonyl)amino)-5-bromopyridine-3-boronic acid pinacol ester; 5-Bromo-2-Boc-aminopyridine-3-boronic acid pinacol ester; 3-Borono-5-bromo-2-(Boc-amino)pyridine pinacol ester; 2-(Boc-amino)-5-bromo-3-pyridineboronic acid pinacol ester; 5-Bromo-2-(N-Boc-amino)pyridin-3-ylboronic acid pinacol ester; Boc-5-Bromo-2-aminopyridine-3-Boronic Acid Pinacol Ester; CAS 1263142-42-2
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-tert-Butyloxycarbonylamino Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.