Description

Imidazo[1,2-A]Pyridine, 3-Bromo-8-(Trifluoromethyl)- is a high-value brominated and trifluoromethylated heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its core value lies in enabling the synthesis of complex molecules with enhanced biological activity and metabolic stability. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that leverage the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLED emitters or charge-transport molecules, due to its fused heterocyclic structure.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, or Buchwald-Hartwig couplings to build molecular complexity.
• Library Synthesis for HTS: A valuable building block for generating diverse compound libraries used in high-throughput screening campaigns.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine, 3-Bromo-8-(Trifluoromethyl)-
CAS No.	1263061-60-4
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	3-Bromo-8-(trifluoromethyl)imidazo[1,2-a]pyridine; 8-(Trifluoromethyl)-3-bromoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 3-bromo-8-(trifluoromethyl)-; 1263061-60-4; 3-Bromo-8-trifluoromethylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Every batch of Imidazo[1,2-A]Pyridine, 3-Bromo-8-(Trifluoromethyl)- is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical R&D and scale-up processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.