Description

1-Propanesulfonamide, n-[3-[[5-Bromo-1-(2,6-Dichlorobenzoyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]Carbonyl]-2,4-Difluorophenyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role in the synthesis of targeted therapeutic agents, particularly in oncology and antiviral research. It is primarily needed by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other targeted cancer therapies.
• Biochemical Research: Used as a reference standard or probe molecule in enzymatic and cellular pathway studies.
• Drug Discovery & Development: Serves as a core scaffold for structure-activity relationship (SAR) optimization in medicinal chemistry programs.
• Preclinical Studies: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for cutting-edge chemical biology and therapeutic discovery projects.

Basic Information

Product Name	1-Propanesulfonamide, n-[3-[[5-Bromo-1-(2,6-Dichlorobenzoyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]Carbonyl]-2,4-Difluorophenyl]-
CAS No.	1262985-24-9
Molecular Formula	C24H14BrCl2F2N3O3S
Molecular Weight	618.26 g/mol
Synonyms	N-[3-[[5-Bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; 1262985-24-9; 1-Propanesulfonamide, N-[3-[(5-bromo-1-[(2,6-dichlorophenyl)carbonyl]-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-; UNII-6Q8K8G8B4F; 6Q8K8G8B4F; SCHEMBL23306277; BDBM50389371; AKOS040759623
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical research and development applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. We support development needs with custom synthesis and purification services to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if necessary. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.