Description

1-Propanesulfonamide, n-[3-[[5-(4-Chlorophenyl)-1-(2,6-Dichlorobenzoyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]Carbonyl]-2,4-Difluorophenyl]- is a high-purity, complex heterocyclic sulfonamide derivative designed for advanced research and development. This compound is of significant value as a key synthetic intermediate or a potential pharmacologically active scaffold in modern drug discovery programs. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in oncology and other disease areas targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors.
• Biochemical Research: Used as a reference standard or a probe compound in biological assays to study protein-ligand interactions and cellular signaling pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for preclinical and clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	1-Propanesulfonamide, n-[3-[[5-(4-Chlorophenyl)-1-(2,6-Dichlorobenzoyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]Carbonyl]-2,4-Difluorophenyl]-
CAS No.	1262985-23-8
Molecular Formula	C30H18Cl3F2N3O3S
Molecular Weight	648.90 g/mol
Synonyms	N-[3-[[5-(4-Chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; 1262985-23-8; UNII-6Q7F4W8V3I; 6Q7F4W8V3I; 1-Propanesulfonamide, N-[3-[[5-(4-chlorophenyl)-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-; BDBM50391457; AKOS025310065; CS-0446645.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.