Description

3-Chloro-5-Difluoromethoxy-Pyridine-2-Carboxylic Acid is a high-value pyridine derivative and a key synthetic intermediate in modern organic chemistry. Its unique structure, featuring chloro, difluoromethoxy, and carboxylic acid functional groups, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine core and halogen substituents.
• Ligand and Catalyst Development: Used in research to create novel ligands for metal catalysis or as a scaffold for functional materials science applications.
• Chemical Research & Development: Employed in academic and industrial R&D settings for exploring new chemical reactions and synthesizing libraries of compounds for biological screening.

Basic Information

Product Name	3-Chloro-5-Difluoromethoxy-Pyridine-2-Carboxylic Acid
CAS No.	1262860-72-9
Molecular Formula	C7H4ClF2NO3
Molecular Weight	223.56 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-chloro-5-(difluoromethoxy)-; 3-Chloro-5-(difluoromethoxy)picolinic acid; 3-Chloro-5-(difluoromethoxy)pyridine-2-carboxylic acid; 1262860-72-9; 3-Chloro-5-difluoromethoxy-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 3-Chloro-5-Difluoromethoxy-Pyridine-2-Carboxylic Acid is monitored through in-process controls and final release testing via modern analytical techniques including HPLC, GC, and NMR to ensure batch-to-batch consistency and high purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.