Description

2-Chloro-3-Fluoro-4-(Difluoromethyl)Pyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and insecticides, where the difluoromethyl and halogen groups contribute to bioactivity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty chemicals, liquid crystals, and functional polymers requiring specific fluorine-containing motifs.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological mechanisms and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-3-Fluoro-4-(Difluoromethyl)Pyridine
CAS No.	1262413-59-1
Molecular Formula	C7H5ClF3N
Molecular Weight	183.57 g/mol
Synonyms	4-(Difluoromethyl)-2-chloro-3-fluoropyridine; 2-Chloro-3-fluoro-4-(difluoromethyl)pyridine; 2-Chloro-3-fluoro-4-difluoromethylpyridine; Pyridine, 2-chloro-3-fluoro-4-(difluoromethyl)-; 1262413-59-1
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluoro-4-(Difluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.