Description

5-Bromo-3-Fluoro-2-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and a trifluoromethyl group on the pyridine ring, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, and advanced polymers with specific electronic or surface properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Functional Group Transformation: Utilized in medicinal chemistry for further functionalization, enabling the exploration of diverse chemical space around the pyridine core.

Basic Information

Product Name	5-Bromo-3-Fluoro-2-(Trifluoromethyl)Pyridine
CAS No.	1262412-30-5
Molecular Formula	C7H2BrF4N
Molecular Weight	243.99 g/mol
Synonyms	2-(Trifluoromethyl)-5-bromo-3-fluoropyridine; 3-Fluoro-5-bromo-2-(trifluoromethyl)pyridine; 5-Bromo-3-fluoro-2-trifluoromethylpyridine; Pyridine, 5-bromo-3-fluoro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-Fluoro-2-(Trifluoromethyl)Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC-MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.