Description

1-Piperidinecarboxylic Acid, 4-Amino-4-(Hydroxymethyl)-, Phenylmethyl Ester is a high-purity, functionalized piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates both amino and hydroxymethyl functionalities, enabling its use in the creation of complex pharmacophores and specialty chemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a precursor in the development of new crop protection agents and pesticides.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and ligands for catalysis.
• Bioconjugation & Probe Development: The reactive amino and hydroxyl groups make it suitable for developing biochemical probes and conjugation linkers.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-Amino-4-(Hydroxymethyl)-, Phenylmethyl Ester
CAS No.	1262412-22-5
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	4-Amino-4-(hydroxymethyl)piperidine-1-carboxylic acid benzyl ester; Benzyl 4-amino-4-(hydroxymethyl)piperidine-1-carboxylate; 4-(Aminomethyl)-4-hydroxypiperidine-1-carboxylic acid benzyl ester; 1-N-CBZ-4-amino-4-hydroxymethylpiperidine; 1-Carbobenzyloxy-4-amino-4-hydroxymethylpiperidine; 4-Amino-4-(hydroxymethyl)-1-piperidinecarboxylic acid phenylmethyl ester; 1-N-Cbz-4-amino-4-(hydroxymethyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-Amino-4-(Hydroxymethyl)-, Phenylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards in research and cGMP-compliant development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.