Description

Imidazo[1,2-A]Pyridine-8-Carboxylic Acid, 3-Iodo-, Ethyl Ester is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique fused-ring structure and iodine substituent enable precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new crop protection agents and herbicides, leveraging its heterocyclic core.
• Material Science Precursor: Serves as a specialized monomer or precursor for creating organic electronic materials and advanced polymers.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and labeled compounds for biological target identification and validation.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex substituents.
• Academic & Contract Research: A valuable reagent for academic research and contract research organizations (CROs) focused on novel heterocyclic chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	Imidazo[1,2-A]Pyridine-8-Carboxylic Acid, 3-Iodo-, Ethyl Ester
CAS No.	1262409-63-1
Molecular Formula	C11H9IN2O2
Molecular Weight	328.11 g/mol
Synonyms	3-Iodoimidazo[1,2-a]pyridine-8-carboxylic acid ethyl ester; Ethyl 3-iodoimidazo[1,2-a]pyridine-8-carboxylate; 8-Ethoxycarbonyl-3-iodoimidazo[1,2-a]pyridine; 3-Iodo-8-ethoxycarbonylimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-8-carboxylic acid, 3-iodo-, ethyl ester; 1262409-63-1; AI3-63531
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) with each batch, detailing purity and identity confirmation. Our quality management system is designed to meet the stringent requirements of GMP and ISO guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.