Description

Methyl 2-Bromo-4-Fluoro-6-Methylbenzoate is a high-purity, multi-functional halogenated benzoate ester serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile molecular scaffold for constructing complex pharmacophores and agrochemicals, enabling precise structural modifications. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialty polymers and liquid crystals with unique optical or electronic properties.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying enzyme mechanisms and protein-ligand interactions in research settings.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 2-Bromo-4-Fluoro-6-Methylbenzoate
CAS No.	1262396-04-2
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-Bromo-4-fluoro-6-methylbenzoic acid methyl ester; Methyl 2-bromo-4-fluoro-6-methylbenzoate; Benzoic acid, 2-bromo-4-fluoro-6-methyl-, methyl ester; Methyl α-bromo-γ-fluoro-m-toluate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-4-Fluoro-6-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.