Description

Methyl 6-Methoxy-5-(4-Methyl-1H-Imidazol-1-Yl)Pyridine-2-Carboxylate CAS NO 1262197-81-8 is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyridine and imidazole moieties. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with targeted biological activity.
• API Synthesis: A key building block for constructing the core scaffold of potential APIs, enabling the introduction of specific functional groups essential for drug efficacy.
• Biochemical Tool Compound: Can be utilized in biochemical assays and as a probe to study specific enzyme interactions or receptor binding mechanisms in early-stage drug discovery.
• Custom Synthesis & Scale-Up: Employed by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects, from milligram-scale research to kilogram-scale pilot production.

Basic Information

Product Name	Methyl 6-Methoxy-5-(4-Methyl-1H-Imidazol-1-Yl)Pyridine-2-Carboxylate
CAS No.	1262197-81-8
Molecular Formula	C12H13N3O3
Molecular Weight	247.25 g/mol
Synonyms	6-Methoxy-5-(4-methyl-1H-imidazol-1-yl)picolinic acid methyl ester; Methyl 6-methoxy-5-(4-methylimidazol-1-yl)picolinate; 2-Pyridinecarboxylic acid, 6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-, methyl ester; 5-(4-Methyl-1H-imidazol-1-yl)-6-methoxypicolinic acid methyl ester; 1-(6-Methoxy-5-(methoxycarbonyl)pyridin-3-yl)-4-methyl-1H-imidazole
EINECS	Contact for details

Quality Control

Our Methyl 6-Methoxy-5-(4-Methyl-1H-Imidazol-1-Yl)Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.