Description

5-(3-Chloro-5-Fluorophenyl)Pyridine-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates both a halogenated phenyl ring and a pyridine-carboxylic acid moiety, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a critical building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its chelating pyridine-carboxylate structure.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	5-(3-Chloro-5-Fluorophenyl)Pyridine-3-Carboxylic Acid
CAS No.	1261964-74-2
Molecular Formula	C12H7ClFNO2
Molecular Weight	251.64 g/mol
Synonyms	3-Pyridinecarboxylic acid, 5-(3-chloro-5-fluorophenyl)-; 5-(3-Chloro-5-fluorophenyl)nicotinic acid; 5-(3-Chloro-5-fluorophenyl)-3-pyridinecarboxylic acid; 3-Carboxy-5-(3-chloro-5-fluorophenyl)pyridine; 1261964-74-2; 5-(3-Chloro-5-fluoro-phenyl)-nicotinic acid; 5-(3-Chloro-5-fluorophenyl)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-(3-Chloro-5-Fluorophenyl)Pyridine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up work. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.