Description

Dimethyl 2-(5-Chloro-3-Nitropyridin-2-Yl)Malonate is a high-purity, synthetically valuable pyridine derivative and malonate ester. This compound serves as a critical advanced pharmaceutical intermediate (API) in the synthesis of complex active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents. Its specific molecular architecture makes it a versatile building block for constructing nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and insecticides, leveraging its halogenated nitropyridine core.
• Chemical Research & Development: Employed as a versatile building block for constructing complex heterocyclic compounds in medicinal and synthetic chemistry.
• Material Science: Potential intermediate in the development of specialty chemicals, dyes, and functional materials requiring specific pyridine-based motifs.

Basic Information

Product Name	Dimethyl 2-(5-Chloro-3-Nitropyridin-2-Yl)Malonate
CAS No.	1261956-26-6
Molecular Formula	C11H9ClN2O6
Molecular Weight	300.65 g/mol
Synonyms	Dimethyl (5-chloro-3-nitropyridin-2-yl)malonate; 2-(5-Chloro-3-nitro-2-pyridinyl)propanedioic acid dimethyl ester; Propanedioic acid, 2-(5-chloro-3-nitro-2-pyridinyl)-, dimethyl ester; 5-Chloro-3-nitropyridine-2-ylmalonic acid dimethyl ester; 2-(5-Chloro-3-nitropyridin-2-yl)malonic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(5-Chloro-3-Nitropyridin-2-Yl)Malonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.