Description

2-(4-Boc-Aminophenyl)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group and a carboxylic acid moiety. This compound is critical for the synthesis of complex molecules, particularly in the development of targeted therapies and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific protein-protein interactions.
• API Synthesis: Used in the multi-step production of complex Active Pharmaceutical Ingredients (APIs) requiring protected functional groups.
• Peptidomimetic Research: Serves as a crucial component in the design and construction of peptidomimetics and other bioactive molecules.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.
• Library Synthesis: Used in combinatorial chemistry to create diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-(4-Boc-Aminophenyl)Nicotinic Acid
CAS No.	1261951-56-7
Molecular Formula	C17H18N2O4
Molecular Weight	314.34 g/mol
Synonyms	2-(4-((tert-Butoxycarbonyl)amino)phenyl)nicotinic acid; 2-[4-[(tert-Butoxycarbonyl)amino]phenyl]pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-[4-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-; Boc-4-Aminophenyl Nicotinic Acid; tert-Butyl N-[4-(3-carboxypyridin-2-yl)phenyl]carbamate; 2-(4-Boc-amino-phenyl)-nicotinic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Boc-Aminophenyl)Nicotinic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical R&D and production. Our quality commitment includes comprehensive identity, purity, and impurity profile verification. A Certificate of Analysis (COA) detailing specific results for each lot is provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; ensure appropriate segregation in storage areas. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.