Description

5-(3-Fluoro-4-Methylphenyl)Nicotinic Acid is a high-purity, functionalized nicotinic acid derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and building block in the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its specific fluorinated biphenyl moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and other small molecule therapeutic research.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its structural features for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science: A monomer or additive in the production of advanced polymers with specific optical or electronic properties.
• Chemical Biology: Employed as a probe or tag in biochemical research due to its functional groups.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	5-(3-Fluoro-4-Methylphenyl)Nicotinic Acid
CAS No.	1261946-42-2
Molecular Formula	C13H10FNO2
Molecular Weight	231.22 g/mol
Synonyms	3-Pyridinecarboxylic acid, 5-(3-fluoro-4-methylphenyl)-; 5-(3-Fluoro-4-methylphenyl)pyridine-3-carboxylic acid; 5-(3-Fluoro-p-tolyl)nicotinic acid; Nicotinic acid, 5-(3-fluoro-4-methylphenyl)-; 1261946-42-2; 5-(3-Fluoro-4-methylphenyl)nicotinate
EINECS	Contact for details

Quality Control

Our production of 5-(3-Fluoro-4-Methylphenyl)Nicotinic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes. We support compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.