Description

3-Amino-5-Chloropyridin-2-Ol Hcl is a high-purity pyridine derivative building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme function.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	3-Amino-5-Chloropyridin-2-Ol Hcl
CAS No.	1261906-29-9
Molecular Formula	C5H6ClN2O•HCl
Molecular Weight	195.04 g/mol
Synonyms	3-Amino-5-chloro-2-pyridinol hydrochloride; 5-Chloro-3-amino-2-pyridinol hydrochloride; 2-Hydroxy-3-amino-5-chloropyridine hydrochloride; 3-Amino-5-chloro-2(1H)-pyridinone hydrochloride; 5-Chloro-2-hydroxy-3-aminopyridine hydrochloride; 3-Amino-5-chloro-2-hydroxypyridine HCl; 2-Pyridinol, 3-amino-5-chloro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Chloropyridin-2-Ol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.