Description

5-(4-Chlorophenyl)-2-Methoxynicotinic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure featuring chlorophenyl and methoxynicotinic acid moieties. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and fine chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially in medicinal chemistry programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor or core structure in the development of proprietary APIs.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring structure-activity relationships and novel synthetic pathways.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for specialized applications.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	5-(4-Chlorophenyl)-2-Methoxynicotinic Acid
CAS No.	1261905-29-6
Molecular Formula	C13H10ClNO3
Molecular Weight	263.67 g/mol
Synonyms	2-Methoxy-5-(4-chlorophenyl)nicotinic acid; 5-(p-Chlorophenyl)-2-methoxynicotinic acid; 2-Methoxy-5-(4-chlorophenyl)-3-pyridinecarboxylic acid; Nicotinic acid, 5-(4-chlorophenyl)-2-methoxy-; 1261905-29-6; 5-(4-Chlorophenyl)-2-methoxy-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(4-Chlorophenyl)-2-Methoxynicotinic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.