Description

4-Chloro-6-Methoxypyridin-3-Amine is a high-purity, versatile pyridine derivative building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogenated methoxypyridine structure enables key synthetic transformations. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogen and methoxy substituents for bioactivity.
• Material Science Research: Serves as a precursor for the development of functionalized ligands, catalysts, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development and the construction of complex heterocyclic libraries.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	4-Chloro-6-Methoxypyridin-3-Amine
CAS No.	1261884-16-5
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	3-Amino-4-chloro-6-methoxypyridine; 4-Chloro-6-methoxy-3-pyridinamine; 6-Methoxy-4-chloropyridin-3-amine; 4-Chloro-6-methoxypyridin-3-ylamine; 3-Pyridinamine, 4-chloro-6-methoxy-; 1261884-16-5
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Methoxypyridin-3-Amine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.